Since winning the BBC Radio 2’s New Comedy Award 2011, Barnes has continued to be a regular on the stand-up circuit, playing even bigger venues. She has also appeared on Weekend Wogan’s Children in Need Special and Russell Kane’s Whistlestop Tour for Radio 2, written for Radio 4’s The News Quiz, played on Eddie Izzard’s Laughs in the Park on BBC Two, appeared on Russell Howard’s Good Newson BBC Three, developed her own series with BBC Radio Comedy, and performed at the Latitude Festival, the Edinburgh Festival Fringe and Radio 2 Live in Hyde Park.
In June 2013, Barnes became noted for an article in The Guardian that followed a blog post she had written, where she spoke about how she felt society treated people deemed ugly and her feelings as someone who self-identified as such. she returned to the subject in 2015 as the subject of her Edinburgh Fringe Show.
In November 2013, Barnes joined the cast of the topical show Stand Up for the Week and, in February 2014, appeared on Radio 4’s The Now Show. In November 2014 she appeared on Radio 4’s The News Quiz.
She has also appeared on Mock the Week on BBC Two and Dave’s As Yet Untitled[ alongside Alan Davies, Janet Street-Porter and Michael Ball and in mid-2016 toured New Zealand.
In December 2016, it was announced she was the new host of the show Newsjack